While there were many factors working against me - my age, my characteristic lack of dexterity, my (for the time) toaster-level PC, and my bargain-bin 200 DPI Dell laser mouse - I never let these disadvantages stop me from padding some lucky player's K/D ratio with my ill-fated MAC-10 rushes.
In my younger and more vulnerable years, I spent a lot of time getting shot in the head in Counter-Strike: Source.